Patent: 4,057,617
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Summary for Patent: 4,057,617
| Title: | Method of labeling proteins with technetium |
| Abstract: | Fibrinogen is labeled with .sup.99m Technetium by reducing pertechnetate at a pH of about 11-12 using a solution of stannous chloride in the presence of a base, then contacting the reduced pertechnetate with fibrinogen. Unwanted lower molecular weight impurities are removed; the labeled product suitably adjusted to a pH of 7-8 to form an injectable isotopic tracer solution. |
| Inventor(s): | Abramovici; Jean (Ixelles, 1050 Brussels, BE), Ermans; Andre Marie (Ixelles, 1050 Brussels, BE), Jeghers; Omer (4561 Neufchateau, BE) |
| Application Number: | 05/635,774 |
| Patent Claims: | see list of patent claims |
Details for Patent 4,057,617
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Csl Behring Gmbh | RIASTAP | fibrinogen concentrate (human) | For Injection | 125317 | January 16, 2009 | ⤷ Start Trial | 1995-11-26 |
| Octapharma Pharmazeutika Produktionsges.m.b.h. | FIBRYGA | fibrinogen (human) | For Injection | 125612 | June 07, 2017 | ⤷ Start Trial | 1995-11-26 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
