Last Updated: November 9, 2026

Patent: 11,311,629

Summary for Patent: 11,311,629

Title:	DNA-templated micelle and uses thereof
Abstract:	The present invention discloses a multifunctional DNA-templated micelle system that has a payload carrier of at least a DNA bridge and a functionalized polyethylene glycol (PEG) segment. The micelle can be used to deliver molecules, such as drugs and polynucleotides, to targeted cells for pharmaceutical uses. The PEG segment provides a functional group, such as amine, for ligand conjugation. The DNA-templated micelle of the present invention is highly controllable in size, loading efficiency and tissue targeting, and can carry multiple payloads for targeted combination strategies in cancer therapy, such as gene delivery, gene therapy, and immunotherapy.
Inventor(s):	Kam W. Leong, Yeh-Hsing LAO, Tzu-Chieh HO, Smruthi SURYAPRAKASH
Assignee:	Columbia University in the City of New York
Application Number:	US16/492,320
Patent Claims:	see list of patent claims

Details for Patent 11,311,629

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Modernatx, Inc.	SPIKEVAX	covid-19 vaccine, mrna	Injection	125752	January 31, 2022	⤷ Start Trial	2038-02-27
Modernatx, Inc.	SPIKEVAX	covid-19 vaccine, mrna	Injection	125752	September 11, 2023	⤷ Start Trial	2038-02-27
Modernatx, Inc.	SPIKEVAX	covid-19 vaccine, mrna	Injection	125752	July 9, 2025	⤷ Start Trial	2038-02-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,311,629

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Country	Patent Number	Estimated Expiration
United States of America	2021128746	⤷ Start Trial
United States of America	2022313839	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2018164883	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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