Last Updated: June 12, 2026

Patent: 10,751,399


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Summary for Patent: 10,751,399
Title:Chimeric antigen receptors that bind to SSEA4 and uses thereof
Abstract:An isolated nucleic acid that contains a nucleotide sequence that encodes the polypeptide of SEQ ID NO: 3. The polypeptide of SEQ ID NO: 3 specifically binds to stage-specific embryonic antigen 4 (SSEA4). Also disclosed is a recombinant cell comprising the isolated nucleic acid described above, a viral vector containing the above isolated nucleic acid, and an isolated polypeptide including the sequence of SEQ ID NO: 3. Provided as well is a chimeric antigen receptor (CAR) that includes a single chain Fv having the sequence of SEQ ID NO: 3 and specifically binding to SSEA4. Moreover, a method is disclosed for treating a tumor by transducing in vitro the T cells of a subject having a tumor expressing SSEA4 with a vector that encodes the CAR, expanding the transduced T cells, and infusing the expanded transduced T cells into the subject, whereby an anti-tumor T cell response is raised.
Inventor(s):Lan Bo Chen
Assignee: Cho Pharma Usa Inc
Application Number:US15/926,382
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

United States Patent 10,751,399 Claims and US Patent Landscape (Critical Analysis)

Executive summary: US Patent 10,751,399 is a US-granted IP asset whose enforceable scope is defined primarily by its independent claim set and limited by where the specification anchors key claim elements. The surrounding landscape in the US typically turns on (1) whether later patents claim the same technical “core” as earlier priority filings, (2) whether additional dependent claims are supported enough to withstand claim-construction narrowing, and (3) whether any terminal disclaimers, continuation practice, or related family members constrain claim breadth.

However, no dataset in the current prompt identifies the patent’s title, assignee, priority, claim text, CPC classes, or cited references. Without the actual claim wording and bibliographic record for US 10,751,399, a complete, accurate, and actionable analysis of claims and the US landscape cannot be produced.

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Details for Patent 10,751,399

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Sanofi-aventis U.s. Llc ZALTRAP ziv-aflibercept Injection 125418 August 03, 2012 ⤷  Start Trial 2038-03-20
Pfizer Inc. ABRYSVO respiratory syncytial virus vaccine Injection 125769 May 31, 2023 ⤷  Start Trial 2038-03-20
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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