Last Updated: November 8, 2026

Patent: 10,729,746

Summary for Patent: 10,729,746

Title:	Recombinant placenta growth factor for treating Duchenne muscular dystrophy
Abstract:	The present invention provides, among other things, methods and compositions for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of a recombinant PLGF protein such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset. The present invention also provides exemplary recombinant PLGF proteins including monomeric, dimeric and single-chain PLGF proteins.
Inventor(s):	Angela Norton, Michael F. Concino, Muthuraman Meiyappan, Andrea Iskenderian
Assignee:	Takeda Pharmaceutical Co Ltd
Application Number:	US14/763,783
Patent Claims:	see list of patent claims

Details for Patent 10,729,746

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	November 23, 2004	⤷ Start Trial	2034-01-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,729,746

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Country	Patent Number	Estimated Expiration
European Patent Office	2948164	⤷ Start Trial
European Patent Office	3586867	⤷ Start Trial
United States of America	2015368309	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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