Last Updated: September 24, 2026

Patent: 10,519,208

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Summary for Patent: 10,519,208

Title:	CD40L single-chain fusion polypeptides and encoding nucleic acids
Abstract:	The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
Inventor(s):	Oliver Hill, Christian Gieffers, Meinolf Thiemann
Assignee:	Apogenix AG
Application Number:	US16/289,361
Patent Claims:	see list of patent claims

Details for Patent 10,519,208

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Takeda Pharmaceuticals U.s.a., Inc.	VONVENDI	von willebrand factor (recombinant)	For Injection	125577	8-Dec-15	10,519,208	2039-02-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,519,208

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Country	Patent Number	Estimated Expiration
Canada	2731388	⤷ Start Trial
Canada	2910512	⤷ Start Trial
Canada	3092223	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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