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Last Updated: September 30, 2020

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Patent: 10,329,314

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Summary for Patent: 10,329,314
Title:Soluble C5aR antagonists
Abstract: Compounds are provided to modulate the C5a receptor. The compounds have the following Formula (I): ##STR00001## including stereoisomers and pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2 and R.sup.3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Inventor(s): Fan; Pingchen (Fremont, CA), Krasinski; Antoni (Sunnyvale, CA), Mali; Venkat Reddy (Cupertino, CA), Miao; Shichang (Foster City, CA), Punna; Sreenivas (Sunnyvale, CA), Song; Yang (Foster City, CA), Stella; Valentino J. (Lawrence, KS), Zeng; Yibin (Foster City, CA), Zhang; Penglie (Foster City, CA)
Assignee: ChemoCentryx, Inc. (Mountain View, CA)
Application Number:15/908,508
Patent Claims:see list of patent claims

Details for Patent 10,329,314

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Chiron PROLEUKIN aldesleukin VIAL 103293 001 1992-05-05   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 001 1998-05-12   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 002 1998-05-12   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX search
Eisai Inc ONTAK denileukin diftitox VIAL 103767 001 1999-02-05   Start Trial ChemoCentryx, Inc. (Mountain View, CA) 2036-04-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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