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Last Updated: December 2, 2021

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Patent: 10,328,130

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Summary for Patent: 10,328,130
Title:Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
Abstract: Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and disorders. In one example, the products include an additional agent or treatment. Such products can be used in methods for administering the products to treat the hyaluronan-associated diseases and conditions, for example, hyaluronan-associated cancers, for example, hyaluronan-rich tumors. The methods include administration of the hyaluronan degrading enzyme composition alone or in combination with other treatments. Also provided are methods and compositions for providing sustained treatment effects in hyaluronan-associated diseases and conditions.
Inventor(s): Frost; Gregory I. (Del Mar, CA), Jiang; Ping (San Diego, CA), Thompson; Curtis B. (Encinitas, CA)
Assignee: Halozyme, Inc. (San Diego, CA)
Application Number:13/385,528
Patent Claims:see list of patent claims

Details for Patent 10,328,130

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-05-05 ⤷  Free Forever Trial 2028-04-14
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-12-02 ⤷  Free Forever Trial 2028-04-14
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 2004-10-26 ⤷  Free Forever Trial 2028-04-14
Akorn, Inc. HYDASE hyaluronidase Injection 021716 2005-10-25 ⤷  Free Forever Trial 2028-04-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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