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Last Updated: September 20, 2020

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Patent: 10,328,130

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Summary for Patent: 10,328,130
Title:Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
Abstract: Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and disorders. In one example, the products include an additional agent or treatment. Such products can be used in methods for administering the products to treat the hyaluronan-associated diseases and conditions, for example, hyaluronan-associated cancers, for example, hyaluronan-rich tumors. The methods include administration of the hyaluronan degrading enzyme composition alone or in combination with other treatments. Also provided are methods and compositions for providing sustained treatment effects in hyaluronan-associated diseases and conditions.
Inventor(s): Frost; Gregory I. (Del Mar, CA), Jiang; Ping (San Diego, CA), Thompson; Curtis B. (Encinitas, CA)
Assignee: Halozyme, Inc. (San Diego, CA)
Application Number:13/385,528
Patent Claims:see list of patent claims

Details for Patent 10,328,130

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Halozyme, Inc. (San Diego, CA) 2028-04-14 DISCN search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Halozyme, Inc. (San Diego, CA) 2028-04-14 DISCN search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Halozyme, Inc. (San Diego, CA) 2028-04-14 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial Halozyme, Inc. (San Diego, CA) 2028-04-14 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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