Last Updated: August 9, 2026

Patent: 10,105,415

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Summary for Patent: 10,105,415

Title:	Compositions comprising granulocyte-macrophage colony-stimulating factor for the treatment of inflammatory bowel disease
Abstract:	The present invention provides compositions comprising granulocyte-macrophage colony-stimulating factor and fosfomycin for the treatment, prevention or alleviation of an inflammatory bowel disease such as Crohn\'s disease, ulcerative colitis or necrotizing enterocolitis of newborn and premature infants by administration of the compositions into the intestinal lumen.
Inventor(s):	Heslet; Lars (Gentofte, DK), Uttenthal; Lars Otto (Salamanca, ES)
Assignee:	Reponex Pharmaceuticals A/S (Horsholm, DK)
Application Number:	15/328,426
Patent Claims:	see list of patent claims

Details for Patent 10,105,415

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bayer Healthcare Pharmaceuticals Inc.	TRASYLOL	aprotinin	Injection	020304	December 29, 1993	⤷ Start Trial	2035-07-24
Partner Therapeutics, Inc.	LEUKINE	sargramostim	For Injection	103362	March 05, 1991	⤷ Start Trial	2035-07-24
Partner Therapeutics, Inc.	LEUKINE	sargramostim	Injection	103362	March 05, 1991	⤷ Start Trial	2035-07-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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