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Last Updated: March 29, 2024

Patent: 10,004,686


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Summary for Patent: 10,004,686
Title:Lipid construct for delivery of insulin to a mammal
Abstract: The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an extended amphipathic lipid that targets the construct to a receptor displayed by an hepatocyte. The composition can comprise a mixture of free insulin and insulin associated with the complex. The composition can be modified to protect insulin and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading insulin into the composition and recycling various components of the composition. Methods of treating individuals inflicted with diabetes.
Inventor(s): Lau; John R. (Howard, OH), Geho; W. Blair (Wooster, OH)
Assignee: SDG, Inc. (Cleveland, OH)
Application Number:13/916,115
Patent Claims:see list of patent claims

Details for Patent 10,004,686

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company HUMULIN R U-100 insulin human Injection 018780 10/28/1982 ⤷  Try a Trial 2025-05-23
Eli Lilly And Company HUMULIN R U-500 insulin human Injection 018780 12/29/2015 ⤷  Try a Trial 2025-05-23
Eli Lilly And Company HUMULIN R U-100 insulin human Injection 018780 08/06/1998 ⤷  Try a Trial 2025-05-23
Eli Lilly And Company HUMULIN R U-500 insulin human Injection 018780 03/31/1994 ⤷  Try a Trial 2025-05-23
Eli Lilly And Company HUMULIN R U-100 insulin human Injection 018780 05/25/2018 ⤷  Try a Trial 2025-05-23
Novo Nordisk Inc. NOVOLIN R insulin human Injection 019938 06/25/1991 ⤷  Try a Trial 2025-05-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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