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Last Updated: May 15, 2021

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Patent: 10,004,686

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Summary for Patent: 10,004,686
Title:Lipid construct for delivery of insulin to a mammal
Abstract: The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an extended amphipathic lipid that targets the construct to a receptor displayed by an hepatocyte. The composition can comprise a mixture of free insulin and insulin associated with the complex. The composition can be modified to protect insulin and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading insulin into the composition and recycling various components of the composition. Methods of treating individuals inflicted with diabetes.
Inventor(s): Lau; John R. (Howard, OH), Geho; W. Blair (Wooster, OH)
Assignee: SDG, Inc. (Cleveland, OH)
Application Number:13/916,115
Patent Claims:see list of patent claims

Details for Patent 10,004,686

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Mylan Pharms Inc SEMGLEE insulin glargine INJECTABLE;INJECTION 210605 001 2020-06-11   Get Started for $10 SDG, Inc. (Cleveland, OH) 2025-05-23 RX search
Sanofi-aventis Us ADMELOG insulin lispro SOLUTION;INTRAVENOUS, SUBCUTANEOUS 209196 003 2018-10-19   Get Started for $10 SDG, Inc. (Cleveland, OH) 2025-05-23 RX search
Sanofi-aventis Us ADMELOG SOLOSTAR insulin lispro SOLUTION;INTRAVENOUS, SUBCUTANEOUS 209196 002 2018-10-19   Get Started for $10 SDG, Inc. (Cleveland, OH) 2025-05-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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