Last Updated: April 23, 2026

Claims for Patent: 8,858,958

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Summary for Patent: 8,858,958

Title:	Adjuvant comprising aluminum, oligonucleotide and polycation
Abstract:	An immunological adjuvant comprises an aluminum salt, an immunostimulatory oligonucleotide and a polycationic polymer, wherein the oligonucleotide and the polymer ideally associate with each other to form a complex. The adjuvant can be included in a composition with an immunogen e.g. to elicit an immune response that protects against a bacterial disease or a fungal disease.
Inventor(s):	Michele Pallaoro, Derek O'Hagan, Rino Rappuoli
Assignee:	Novartis AG , GSK Vaccines SRL
Application Number:	US12/870,708

Details for Patent 8,858,958

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Biologicals	MENVEO	meningococcal (groups a, c, y, and w-135) oligosaccharide diphtheria crm197 conjugate vaccine	Injection	125300	February 19, 2010	⤷ Start Trial	2030-08-27
Glaxosmithkline Biologicals	MENVEO	meningococcal (groups a, c, y, and w-135) oligosaccharide diphtheria crm197 conjugate vaccine	Injection	125300	October 14, 2022	⤷ Start Trial	2030-08-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,858,958

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Country	Patent Number	Estimated Expiration
Australia	2010288239	⤷ Start Trial
Brazil	112012004276	⤷ Start Trial
Canada	2772103	⤷ Start Trial
China	102740882	⤷ Start Trial
European Patent Office	2470205	⤷ Start Trial
Japan	2013503148	⤷ Start Trial
Japan	2016034980	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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