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Last Updated: April 19, 2024

Claims for Patent: 8,609,112

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Summary for Patent: 8,609,112

Title:	Botulinum toxin treatments of depression
Abstract:	Methods for preventing or treating depression including a depression mediated by the thalamus. Depression, including a thalamically mediated depression, can be treated by peripheral administration of a botulinum toxin to or to the vicinity of a trigeminal sensory nerve, thereby preventing or treating the depression.
Inventor(s):	Blumenfeld; Andrew M. (Del Mar, CA), Turkel; Catherine C. (Newport Coast, CA), Brin; Mitchell F. (Newport Beach, CA)
Assignee:	Allergan, Inc. (Irvine, CA)
Application Number:	13/757,431
Patent Claims:	1. A method for treating depression comprising directly administering a botulinum toxin to one or more nerves of a patient with depression to thereby treat the depression, wherein the one or more nerves are selected from the group consisting of: supra orbital nerve, supra trochlear nerve, lacrimal nerves, infratrochlear nerve, external nasal branch of anterior ethmoidal nerve, and mixtures thereof. 2. The method of claim 1, wherein the botulinum toxin is a botulinum toxin type A. 3. The method of claim 1, wherein the botulinum toxin is a botulinum toxin type B. 4. The method of claim 1, wherein the botulinum toxin is administered by injection. 5. The method of claim 1, wherein the botulinum toxin is administered to the nerve endings. 6. A method for treating depression comprising directly administering a botulinum toxin to one or more nerves of a patient with depression to thereby treat the depression, wherein the one or more nerves are selected from the group consisting of: infraorbital nerve, zygomaticofacial nerve, zygomaticotemporal nerve, and mixtures thereof. 7. The method of claim 6, wherein the botulinum toxin is a botulinum toxin type A. 8. The method of claim 6, wherein the botulinum toxin is a botulinum toxin type B. 9. The method of claim 6, wherein the botulinum toxin is administered by injection. 10. The method of claim 6, wherein the botulinum toxin is administered to the nerve endings. 11. A method for treating depression comprising directly administering a botulinum toxin to one or more nerves of a patient with depression to thereby treat the depression, wherein the one or more nerves are selected from the group consisting of: mental nerve, buccal nerve, auriculotemporal nerve, and mixtures thereof. 12. The method of claim 11, wherein the botulinum toxin is a botulinum toxin type A. 13. The method of claim 11, wherein the botulinum toxin is a botulinum toxin type B. 14. The method of claim 11, wherein the botulinum toxin is administered by injection. 15. The method of claim 11, wherein the botulinum toxin is administered to the nerve endings.

Details for Patent 8,609,112

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Solstice Neurosciences, Llc	MYOBLOC	rimabotulinumtoxinb	Injection	103846	12/08/2000	⤷ Try a Trial	2023-10-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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