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Last Updated: January 1, 2026

Claims for Patent: 8,609,088


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Summary for Patent: 8,609,088
Title:Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
Abstract:The invention provides a method to prevent, inhibit or treat one or more neurological symptoms associated with a lysosomal storage disease in a mammal in need thereof, which includes intranasally administering to the mammal a composition comprising an effective amount of a lysosomal storage enzyme or a recombinant adeno-associated virus vector comprising an open reading frame encoding a lysosomal storage enzyme. Also provided are compositions and devices useful in the methods.
Inventor(s):Daniel A. Wolf, II William H. Frey, R. Scott McIvor, Leah R. Hanson
Assignee: HealthPartners Research and Education , University of Minnesota System
Application Number:US13/465,575

Details for Patent 8,609,088

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Kamada Ltd. VARIZIG varicella zoster immune globulin (human) For Injection 125430 December 20, 2012 8,609,088 2032-05-07
Kamada Ltd. VARIZIG varicella zoster immune globulin (human) Injection 125430 September 29, 2014 8,609,088 2032-05-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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