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Last Updated: December 18, 2025

Claims for Patent: 8,574,578


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Summary for Patent: 8,574,578
Title:Antibodies against PDGFRα to inhibit tumor growth
Abstract:The invention provides antibodies that bind to human PDGFRα and neutralize activation of the receptor. The invention further provides methods for neutralizing activation of PDGFRα and methods of treating a mammal with a neoplastic disease using the antibodies alone or in combination with other agents.
Inventor(s):Nick LOIZOS, Jim Huber
Assignee: ImClone LLC
Application Number:US13/276,353

Details for Patent 8,574,578

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company LARTRUVO olaratumab Injection 761038 October 19, 2016 ⤷  Get Started Free 2031-10-19
Eli Lilly And Company LARTRUVO olaratumab Injection 761038 July 10, 2017 ⤷  Get Started Free 2031-10-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 8,574,578

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2006138729 ⤷  Get Started Free
United States of America 8425911 ⤷  Get Started Free
United States of America 8128929 ⤷  Get Started Free
United States of America 2012034244 ⤷  Get Started Free
United States of America 2012027767 ⤷  Get Started Free
United States of America 2009110678 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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