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Last Updated: December 16, 2025

Claims for Patent: 8,529,908

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Summary for Patent: 8,529,908

Title:	Meningococcal conjugate vaccination
Abstract:	Conjugated meningococcal capsular saccharides will be introduced into immunization schedules in the near future, but the phenomenon of “carrier suppression” must first be addressed, particularly where multiple conjugates are to be used. In the invention, tetanus toxoid is used as the carrier protein, even where multiple meningococcal conjugates are administered at the same time and where a patient has previously been exposed to the carrier protein, either in the form of a previous immunogen (e.g. in a DTP vaccine) or as a previous carrier protein (e.g. in a Hib or pneumococcal conjugate vaccine). The invention provides a method for immunizing a patient, comprising administering multiple conjugates of meningococcal capsular saccharides, wherein each conjugate comprises a tetanus toxoid carrier protein, and the capsular saccharide, and wherein the patient has been pre-immunized with a tetanus toxoid.
Inventor(s):	Cameron John Marshall
Assignee:	GlaxoSmithKline Biologicals SA
Application Number:	US11/795,229

Details for Patent 8,529,908

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Biologicals	MENVEO	meningococcal (groups a, c, y, and w-135) oligosaccharide diphtheria crm197 conjugate vaccine	Injection	125300	February 19, 2010	⤷ Get Started Free	2026-01-13
Glaxosmithkline Biologicals	MENVEO	meningococcal (groups a, c, y, and w-135) oligosaccharide diphtheria crm197 conjugate vaccine	Injection	125300	October 14, 2022	⤷ Get Started Free	2026-01-13
Glaxosmithkline Biologicals	HIBERIX	haemophilus b conjugate vaccine (tetanus toxoid conjugate)	Injection	125347	August 19, 2009	⤷ Get Started Free	2026-01-13
Glaxosmithkline Biologicals	MENHIBRIX	meningococcal groups c and y and haemophilus b tetanus toxoid conjugate vaccine	Injection	125363	June 14, 2012	⤷ Get Started Free	2026-01-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,529,908

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2006075170	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2005105140	⤷ Get Started Free
United States of America	9402915	⤷ Get Started Free
United States of America	2016303215	⤷ Get Started Free
United States of America	2010104593	⤷ Get Started Free
United States of America	2009060945	⤷ Get Started Free
United States of America	10064932	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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