Last Updated: June 12, 2026

Claims for Patent: 8,394,768

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Summary for Patent: 8,394,768

Title:	Synergistic therapeutic use of Prothrombin Complex Concentrates with FVIII concentrates
Abstract:	The field of the invention is the treatment of acquired bleeding, a clinical condition associated with severe traumatic, peri- or post-operative bleeding. A novel treatment is proposed in which synergistic procoagulatory properties of Prothrombin Complex Concentrates (PCC) together with medicaments comprising FVIII and/or vWF are exploited.
Inventor(s):	Gerhard Dickneite
Assignee:	CSL Behring GmbH Deutschland
Application Number:	US12/520,773

Details for Patent 8,394,768

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Csl Behring Gmbh	KCENTRA	prothrombin complex concentrate (human)	For Injection	125421	April 29, 2013	⤷ Start Trial	2027-12-18
Csl Behring Gmbh	KCENTRA	prothrombin complex concentrate (human)	For Injection	125421	November 26, 2013	⤷ Start Trial	2027-12-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,394,768

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Country	Patent Number	Estimated Expiration
Australia	2007338385	⤷ Start Trial
Canada	2673446	⤷ Start Trial
Denmark	2125004	⤷ Start Trial
European Patent Office	1935429	⤷ Start Trial
European Patent Office	2125004	⤷ Start Trial
Spain	2788075	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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