Last Updated: June 30, 2026

Claims for Patent: 8,192,747


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Summary for Patent: 8,192,747
Title:Live attenuated rotavirus vaccine for oral administration
Abstract:This invention provides liquid rotavirus formulations that are suitable for oral administration to human infants. In particular, the invention provides pharmaceutical compositions and vaccines, comprising a rotavirus antigen, a sugar and a carboxylate, wherein said formulation has a pH of between pH 5.0 and pH 8.0 and comprises no phosphate or less than 5 mM phosphate. The invention also provides methods of preparing said rotavirus formulations and use thereof in the prevention or treatment or rotavirus associated diseases in humans.
Inventor(s):Vincent Vande Velde
Assignee: GlaxoSmithKline Biologicals SA
Application Number:US11/816,443

Details for Patent 8,192,747

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Glaxosmithkline Biologicals ROTARIX rotavirus vaccine, live, oral For Suspension 125265 April 03, 2008 8,192,747 2026-02-15
Glaxosmithkline Biologicals ROTARIX rotavirus vaccine, live, oral Suspension 125265 November 04, 2022 8,192,747 2026-02-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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