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Last Updated: April 2, 2026

Claims for Patent: 8,182,836


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Summary for Patent: 8,182,836
Title:Abuse-resistant oral dosage forms and method of use thereof
Abstract:An opioid-antagonist oral dosage form which does not release a therapeutically effective amount of the opioid antagonist when the oral dosage form is orally administered to a human being, but whereby a physical alteration of the oral dosage form results in a release of the therapeutically effective amount of the opioid antagonist. An embodiment of the oral dosage form includes an opioid-antagonist layer coated onto a biologically inert pellet, and a non-releasing membrane coated onto the opioid-antagonist layer. Optionally, the oral dosage form can also include an opioid agonist, such that a method of preventing the abuse of an oral dosage form of an opioid agonist is provided by forming the oral dosage form including an opioid agonist and an opioid antagonist.
Inventor(s):Atul M. Mehta
Assignee: Elite Laboratories Inc
Application Number:US12/478,952

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