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Last Updated: December 29, 2025

Claims for Patent: 8,105,607


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Summary for Patent: 8,105,607
Title:Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
Abstract:The present invention features the use of PorB polypeptide as a therapeutic agent. In specific embodiment the invention features a chlamydial vaccine based on a PorB polypeptide, as well as methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila. The invention further features methods for identifying agents that affect PorB function (such as in transport of α-ketoglutarate and which are effective as anti-chlamydial chemotherapeutic agents.
Inventor(s):Richard S. Stephens, Aya Kubo
Assignee: University of California San Diego UCSD
Application Number:US11/100,352

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