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Last Updated: December 30, 2025

Claims for Patent: 7,935,341

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Summary for Patent: 7,935,341

Title:	Antibodies to complementary peptides of thrombin or portions thereof
Abstract:	Disclosed are antibodies and antigen-binding fragments that bind to a complementary peptide having an amino acid sequence that is encoded by the complement of a nucleotide sequence encoding thrombin or a portion thereof. Such antibodies and antigen-binding fragments can be agonists or antagonists of thrombin receptor-mediated events. Also disclosed are methods of using the agonist antibodies and antigen-binding fragments of the invention to activate the non-proteolytically activated thrombin receptor (NPAR) in a subject in need of such treatment. In addition, methods of using the antagonist antibodies and antigen-binding fragments of the invention to inhibit activation of the NPAR in a subject in need of such treatment are disclosed.
Inventor(s):	Darrell H. Carney, John S. Bergmann, Gerald M. Fuller
Assignee:	Capstone Holding Corp
Application Number:	US11/521,596

Details for Patent 7,935,341

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Alexion Pharmaceuticals, Inc.	SOLIRIS	eculizumab	Injection	125166	March 16, 2007	7,935,341	2026-09-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,935,341

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2007035406	⤷ Get Started Free
United States of America	2008241149	⤷ Get Started Free
European Patent Office	1934262	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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