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Last Updated: December 31, 2025

Claims for Patent: 7,928,064


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Summary for Patent: 7,928,064
Title:Transgenically produced antithrombin III
Abstract:This invention relates to transgenically produced human Antithrombin III (tgATIII). The human ATIII produced by the transgenic process of the present invention has a monosaccharide composition which comprises N-acetylgalactosamine (GalNAc) along with fucose, N-acetylglucosamine, galactose, mannose, and N-acetylneuraminic acid/N-glycolyneuraminic acid. The monosaccharide composition differs with that of plasma derived ATIII (phATIII). It has been found that tgATIII has an increased clearance rate when compared to phATIII.
Inventor(s):Paul DiTullio, Harry M. Meade, Edward S. Cole
Assignee: rEVO Biologics Inc
Application Number:US11/284,585

Details for Patent 7,928,064

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Revo Biologics, Inc. ATRYN antithrombin (recombinant) For Injection 125284 February 06, 2009 ⤷  Get Started Free 2025-11-14
Revo Biologics, Inc. ATRYN antithrombin (recombinant) For Injection 125284 April 11, 2014 ⤷  Get Started Free 2025-11-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 7,928,064

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 9626268 ⤷  Get Started Free
United States of America 7019193 ⤷  Get Started Free
United States of America 6441145 ⤷  Get Started Free
United States of America 5843705 ⤷  Get Started Free
United States of America 2008176786 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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