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Last Updated: December 19, 2025

Claims for Patent: 7,862,820

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Summary for Patent: 7,862,820

Title:	Immunoglobulin chimeric monomer-dimer hybrids
Abstract:	The invention relates to a chimeric monomer-dimer hybrid protein that comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first polypeptide chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Inventor(s):	Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low
Assignee:	Bioverativ Therapeutics Inc
Application Number:	US11/588,431

Details for Patent 7,862,820

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bioverativ Therapeutics, Inc.	ELOCTATE	antihemophilic factor (recombinant), fc fusion protein	For Injection	125487	June 06, 2014	⤷ Get Started Free	2026-10-27
Bioverativ Therapeutics, Inc.	ELOCTATE	antihemophilic factor (recombinant), fc fusion protein	For Injection	125487	January 27, 2017	⤷ Get Started Free	2026-10-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,862,820

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2006074199	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2005001025	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2004101739	⤷ Get Started Free
United States of America	9725496	⤷ Get Started Free
United States of America	9636416	⤷ Get Started Free
United States of America	8932830	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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