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Last Updated: December 19, 2025

Claims for Patent: 7,404,956


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Summary for Patent: 7,404,956
Title:Immunoglobulin chimeric monomer-dimer hybrids
Abstract:The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Inventor(s):Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low
Assignee: Bioverativ Therapeutics Inc
Application Number:US10/841,250

Details for Patent 7,404,956

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bioverativ Therapeutics, Inc. ALPROLIX coagulation factor ix (recombinant), fc fusion protein For Injection 125444 March 28, 2014 7,404,956 2024-05-06
Bioverativ Therapeutics, Inc. ALPROLIX coagulation factor ix (recombinant), fc fusion protein For Injection 125444 February 18, 2016 7,404,956 2024-05-06
Bioverativ Therapeutics, Inc. ALPROLIX coagulation factor ix (recombinant), fc fusion protein For Injection 125444 July 14, 2016 7,404,956 2024-05-06
Bioverativ Therapeutics, Inc. ELOCTATE antihemophilic factor (recombinant), fc fusion protein For Injection 125487 June 06, 2014 7,404,956 2024-05-06
Bioverativ Therapeutics, Inc. ELOCTATE antihemophilic factor (recombinant), fc fusion protein For Injection 125487 January 27, 2017 7,404,956 2024-05-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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