Last Updated: April 23, 2026

Claims for Patent: 7,351,533

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Summary for Patent: 7,351,533

Title:	In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents
Abstract:	A method of disassembly/reassembly of papillomavinis VLPs is provided. The resultant VLPs have enhanced homogeneity, present conformational, neutralizing PV epitopes, and therefore are useful prophylactic and diagnostic agents. Further, these VLPs can be used to encapsulate desired moieties, e.g., therapeutic or diagnostic agents, or marker” DNAs, and the resultant VLPs used as in vivo delivery vehicles or as pseudovirions for evaluating vaccine efficacy.
Inventor(s):	Michael P. McCarthy, JoAnne A. Suzich
Assignee:	MedImmune LLC
Application Number:	US10/762,928

Details for Patent 7,351,533

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Biologicals	CERVARIX	human papillomavirus bivalent (types 16 and 18) vaccine, recombinant	Injection	125259	October 16, 2009	7,351,533	2024-01-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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