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Last Updated: December 19, 2025

Claims for Patent: 7,348,004


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Summary for Patent: 7,348,004
Title:Immunoglobulin chimeric monomer-dimer hybrids
Abstract:The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Inventor(s):Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low, James Stattel
Assignee: Bioverativ Therapeutics Inc
Application Number:US11/029,003

Details for Patent 7,348,004

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bioverativ Therapeutics, Inc. ELOCTATE antihemophilic factor (recombinant), fc fusion protein For Injection 125487 June 06, 2014 ⤷  Get Started Free 2025-01-05
Bioverativ Therapeutics, Inc. ELOCTATE antihemophilic factor (recombinant), fc fusion protein For Injection 125487 January 27, 2017 ⤷  Get Started Free 2025-01-05
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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