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Last Updated: April 19, 2024

Claims for Patent: 6,835,809

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Summary for Patent: 6,835,809

Title:	Thrombopoietic compounds
Abstract:	The invention relates to the field of compounds, especially peptides or polypeptides, that have thrombopoietic activity. The peptides and polypeptides of the invention may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal.
Inventor(s):	Liu; Chuan-Fa (Longmont, CO), Feige; Ulrich (Newbury Park, CA), Cheetham; Janet C. (Montecito, CA)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	09/422,838
Patent Claims:	1. A compound that binds to an Mp1 receptor comprising the structure wherein TMP.sub.1, and TMP.sub.2 are each Ile-Glu-Gly-Pro-Thr-Leu-Arg-Gln-Trp-Leu-Ala-Ala-Arg-Ala. (SEQ ID NO: 1); L.sub.1 is a linker; and n is 0 or 1; and physiologically acceptable salts thereof. 2. A compound that binds to an Mp1 receptor, which is selected from the group consisting of ##STR6## 3. A compound that binds to an Mp1 receptor, which is selected from the group consisting of ##STR7## and physiologically acceptable salts thereof.

Details for Patent 6,835,809

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen, Inc.	NPLATE	romiplostim	For Injection	125268	08/22/2008	⤷ Try a Trial	2018-10-23
Amgen, Inc.	NPLATE	romiplostim	For Injection	125268	10/17/2019	⤷ Try a Trial	2018-10-23
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 6,835,809

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Country	Patent Number	Estimated Expiration
Argentina	020934	⤷ Try a Trial
Austria	348163	⤷ Try a Trial
Australia	1223900	⤷ Try a Trial
Australia	773891	⤷ Try a Trial
Bulgaria	105401	⤷ Try a Trial
Bulgaria	110221	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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