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Last Updated: April 2, 2026

Claims for Patent: 6,835,809

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Summary for Patent: 6,835,809

Title:	Thrombopoietic compounds
Abstract:	The invention relates to the field of compounds, especially peptides or polypeptides, that have thrombopoietic activity. The peptides and polypeptides of the invention may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal.
Inventor(s):	Liu; Chuan-Fa (Longmont, CO), Feige; Ulrich (Newbury Park, CA), Cheetham; Janet C. (Montecito, CA)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	09/422,838
Patent Claims:	1. A compound that binds to an Mp1 receptor comprising the structure wherein TMP.sub.1, and TMP.sub.2 are each Ile-Glu-Gly-Pro-Thr-Leu-Arg-Gln-Trp-Leu-Ala-Ala-Arg-Ala. (SEQ ID NO: 1); L.sub.1 is a linker; and n is 0 or 1; and physiologically acceptable salts thereof. 2. A compound that binds to an Mp1 receptor, which is selected from the group consisting of ##STR6## 3. A compound that binds to an Mp1 receptor, which is selected from the group consisting of ##STR7## and physiologically acceptable salts thereof.

Details for Patent 6,835,809

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen Inc.	NPLATE	romiplostim	For Injection	125268	August 22, 2008	⤷ Start Trial	2019-10-22
Amgen Inc.	NPLATE	romiplostim	For Injection	125268	July 22, 2019	⤷ Start Trial	2019-10-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 6,835,809

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Country	Patent Number	Estimated Expiration
Argentina	020934	⤷ Start Trial
Austria	E348163	⤷ Start Trial
Australia	1223900	⤷ Start Trial
Australia	773891	⤷ Start Trial
Bulgaria	105401	⤷ Start Trial
Bulgaria	110221	⤷ Start Trial
Bulgaria	65663	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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