Last Updated: May 1, 2026

Claims for Patent: 6,632,978

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Summary for Patent: 6,632,978

Title:	Transgenic animals for studying regulation of genes
Abstract:	A transgenic non-human animal (e.g., a transgenic mouse) comprising a polynucleotide encoding a soluble marker protein functionally linked to a regulatory sequence of an endogenous gene encoding E-selectin. Also described are methods for detecting modulators of the E-selectin gene using said transgenic non-human animal, and cultured cells obtained therefrom.
Inventor(s):	Edgar Käslin, Marcel Luyten, Hans-Günter Zerwes
Assignee:	Novartis AG
Application Number:	US09/693,011

Details for Patent 6,632,978

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Revo Biologics, Inc.	ATRYN	antithrombin (recombinant)	For Injection	125284	February 06, 2009	⤷ Start Trial	2020-10-20
Revo Biologics, Inc.	ATRYN	antithrombin (recombinant)	For Injection	125284	April 11, 2014	⤷ Start Trial	2020-10-20
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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