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Last Updated: December 17, 2025

Claims for Patent: 6,602,684


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Summary for Patent: 6,602,684
Title:Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
Abstract:The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that includes a region equivalent to the Fc region of an immunoglobulin, with enhanced Fc-mediated cellular cytotoxicity.
Inventor(s):Pablo Umaña, Joël Jean-Mairet, James E. Bailey
Assignee: Roche Glycart AG
Application Number:US09/294,584

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