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Last Updated: November 30, 2020

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Claims for Patent: 6,355,006

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Summary for Patent: 6,355,006
Title: Method and apparatus for cartilage growth stimulation
Abstract:A kit of elements including an ultrasonic generator, transducers with connecting cables, and a means for locating the transducers over areas of the body containing cartilage, is provided with the surgical instruments for post-surgical application to ultrasonically stimulate the cartilage growth, thus relieving the effects of surgical intervention.
Inventor(s): Ryaby; John P. (Essex Falls, NJ), Talish; Roger J. (Hillsborough, NJ), Rose; Emery (Astoria, NY), Winder; Alan A. (Westport, CT), Urgovitch, Sr.; Kenneth (Clifton, NJ)
Assignee: Exogen, Inc. (Piscataway, NJ)
Application Number:09/436,999
Patent Claims:1. A kit for ultrasonically stimulating cartilage growth, which comprises:

means for initiating a biological healing response at or adjacent a cartilaginous site;

an ultrasonic transducer assembly having at least one ultrasonic transducer;

a placement module configured to be worn by a patient, said placement module being configured to receive said transducer assembly such that when said placement module is worn said at least one ultrasonic transducer is positioned in proximity to the channels;

an ultrasonic signal generator positioned in said ultrasonic transducer assembly; and

a main operating unit.

2. The kit according to claim 1, wherein the means for initiating the biological healing response includes a drill assembly.

3. The kit according to claim 1, wherein the means for initiating the biological healing response includes a laser drill assembly.

4. The kit according to claim 1, wherein the means for initiating the biological healing response includes a scraping assembly.

5. The kit according to claim 1, wherein the means for initiating the biological healing response includes a chemical substance for irradiating the cartilaginous site.

6. The kit according to claim 1, wherein said ultrasonic signal generator includes signal generator circuitry and an internal power source connected to said signal generator circuitry, a display coupled to said signal generator circuitry to display treatment sequence data, and said signal generator circuitry including a processor and means for generating a pulsed RF signal.

7. The kit according to claim 1, further comprising safety interlock means to prevent inadvertent excitation of said at least one ultrasonic transducer.

8. The kit according to claim 1, wherein said placement module includes a locking mechanism which when worn by the patient prevents the patient from bending or extending the limbs.

9. The kit according to claim 1, wherein the placement module is constructed from a conductive material and said at least one ultrasonic transducer is provided on said placement module is electrically coupled to said main operation unit via said conductive material.

10. The kit according to claim 1, wherein the placement module is custom molded for a particular joint of the patient.

11. The kit according to claim 1, wherein at least one ultrasonic transducer includes means for receiving reflected diagnostic data.

12. A method for ultrasonically stimulating a healing response for the regeneration of cartilage comprising the following steps:

initiating a biological healing response at or adjacent a cartilaginous site;

providing a main operating unit having an internal power source coupled to an ultrasonic transducer assembly, said ultrasonic transducer assembly includes at least one ultrasonic transducer, an ultrasonic signal generator and signal generator circuitry therein;

providing a placement module configured to receive said transducer assembly such that when said placement module is secured to a patient's body said at least one ultrasonic transducer is positioned in proximity to the channels; and

exciting said at least one ultrasonic transducer to impinge ultrasonic waves towards the cartilaginous site.

13. The method according to claim 12, wherein the step of initiating the biological healing response includes drilling at least one channel within the bone joint walls at the cartilaginous site.

14. The method according to claim 12, wherein the step of initiating the biological healing response is selected from the group consisting of scraping the cartilaginous site, applying a chemical substance to the cartilaginous site, and inducing a fracture at the cartilaginous site.

15. The method according to claim 12, further comprising the step of transplanting non-weight bearing cartilage to the cartilaginous site prior to treatment.

16. The method according to claim 12, further comprising the step of transplanting autologous cultured chondrocytes to the cartilaginous site prior to treatment.

17. The method according to claim 12, further including the step of receiving reflected diagnostic data by said at least one ultrasonic transducer.

18. The method according to claim 12, wherein the step of exciting said at least one ultrasonic transducer to impinge ultrasonic waves towards the cartilaginous site causes the regenerated cartilage to integrate with the non-regenerated cartilage present at the cartilaginous site.

19. A method for ultrasonically stimulating a healing response for the regeneration of cartilage comprising the following steps:

initiating a biological healing response at or adjacent a cartilaginous site;

releasably securing at least one ultrasonic transducer coupled to a signal generator to a band;

affixing the band on a patient such that said at least one transducer is in proximity to an area where the regeneration of cartilage is desired; and

exciting said at least one ultrasonic transducer by actuating said signal generator to impinge ultrasonic waves towards the cartilaginous site.

20. The method according to claim 19, further including the step of:

connecting said at least one ultrasonic transducer to an operating unit, said operating unit having an internal power source.

21. The method according to claim 19, further including the step of receiving reflected diagnostic data by said at least one ultrasonic transducer.

Details for Patent 6,355,006

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Vericel Corporation MACI autologous cultured chondrocytes IMPLANT 125603 001 2017-01-11   Start Trial Exogen, Inc. (Piscataway, NJ) 2017-02-06 search
Vericel Corporation MACI autologous cultured chondrocytes IMPLANT 125603 1 2017-01-11   Start Trial Exogen, Inc. (Piscataway, NJ) 2017-02-06 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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