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Last Updated: March 27, 2026

Claims for Patent: 6,022,544

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Summary for Patent: 6,022,544

Title:	Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
Abstract:	The invention features a method for reducing an undesired antibody response in a mammal by administering to the mammal a non-immunogenic construct which is free of high molecular weight immunostimulatory molecules. The construct which contains at least two copies of a B cell membrane immunoglobulin receptor epitope bound to a pharmaceutically acceptable non-immunogenic carrier directly binds to B cell membrane immunoglobulin receptors but fails to form an immunon.
Inventor(s):	Howard M. Dintzis, Renee Z. Dintzis, James K. Blodgett, John C. Cheronis, Gary Kirschenheuter
Assignee:	Johns Hopkins University
Application Number:	US08/391,267

Details for Patent 6,022,544

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Emergent Biosolutions Canada Inc.	ACCRETROPIN	somatropin	Injection	021538	January 23, 2008	6,022,544	2017-02-08
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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