Claims for Patent: 5,722,952

Summary for Patent: 5,722,952

Title:	Treatment of presbyopia and other eye disorders
Abstract:	Presbyopia and hyperopia are treated by a method which increases the amplitude of accommodation by increasing the effective working distance of the ciliary muscle in the presbyopic eye. The effective working distance of the ciliary muscle can be increased by expanding the sclera in the region of the ciliary body. This expansion is accomplished by suturing to the sclera a relatively rigid band having a diameter slightly greater than that of the sclera in the region of the ciliary body, by weakening the sclera overlying the ciliary body, by surgical procedures or treatment with enzymes, heat or radiation, whereby intraocular pressure expands the weakened sclera, or by surgical alloplasty. The effective working distance of the ciliary muscle can also be increased by shortening the zonules by application of heat or radiation, by repositioning one or both insertions of the ciliary muscle or by shortening the ciliary muscle. Presbyopia is also arrested according to the invention by inhibiting the continued growth of the crystalline lens by application of heat, radiation or antimitotic drugs to the epithelium of the lens. Primary open angle glaucoma and/or ocular hypertension can be prevented/and or treated by increasing the effective working range of the ciliary muscle according to the invention.
Inventor(s):	Schachar; Ronald A. (Denison, TX)
Assignee:
Application Number:	08/462,649
Patent Claims:	1. A method of increasing the amplitude of accommodation of a human eye having a crystalline lens and a ciliary muscle comprising increasing the effective working distance of the ciliary muscle by increasing the radial distance between the equator of the crystalline lens and the inner diameter of the ciliary body by weakening the sclera of the globe in the region overlying the ciliary body through intervention with external means, wherein said sclera is weakened by contact with an enzyme. 2. The method of claim 1 wherein said enzyme is collagenase. 3. The method of claim 1 wherein said enzyme is applied topically to the globe of the eye in the region of the ciliary body. 4. The method of claim 1 wherein said enzyme is injected into the sclera in the region of the ciliary body.

Details for Patent 5,722,952

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965		2015-03-03