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Last Updated: December 17, 2025

Claims for Patent: 5,595,721

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Summary for Patent: 5,595,721

Title:	Radioimmunotherapy of lymphoma using anti-CD20
Abstract:	Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
Inventor(s):	Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
Assignee:	Coulter Corp , GlaxoSmithKline LLC , University of Michigan System
Application Number:	US08/121,582

Details for Patent 5,595,721

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Llc	BEXXAR	tositumomab and iodine i-131 tositumomab	Injection	125011	June 27, 2003	5,595,721	2014-01-21
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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