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Last Updated: April 23, 2024

Claims for Patent: 5,480,640

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Summary for Patent: 5,480,640

Title:	Alpha interferon for treating prostate cancer
Abstract:	Described is a method for treating carcinoma of the prostate using recombinant human alpha interferon via intraprostatic or intralesional injection.
Inventor(s):	Morales; Alvaro (Kingston, CA), Wilson; James W. L. (Kingston, CA)
Assignee:	Schering Corporation (Kenilworth, NJ)
Application Number:	08/432,742
Patent Claims:	1. A method for treating cancer of the prostate comprising administering a therapeutically effective amount of alpha interferon by intraprostatic or intralesional injection. 2. The method of claim 1 wherein the alpha interferon is administered by intraprostatic injection such that the whole prostate is infiltrated. 3. The method of claim 1 wherein the alpha interferon is administered by intralesional injection such that the entire lesion is infiltrated. 4. The method of claim 1 wherein the alpha interferon is selected from interferon alfa-2a, interferon alfa-2b, interferon alfa-2c, interferon alfa-n 1, consensus alfa interferon, and interferon alfa-n3. 5. The method of claim 4 wherein the alpha interferon is interferon alfa-2b. 6. The method of clam 5 wherein the interferon alfa-2b is administered once per week for a period of 5 weeks in progressively increasing dosages. 7. The method of claim 6 wherein the increasing dosages are 1.times.10.sup.6, 2.times.10.sup.6, 3.times.10.sup.6, 4.times.10.sup.6, and 5.times.10.sup.6 I.U.

Details for Patent 5,480,640

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2039-03-29
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2039-03-29
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2039-03-29
Hemispherx Biopharma, Inc.	ALFERON N INJECTION	interferon alfa-n3 (human leukocyte derived)	Injection	103158	10/10/1989	⤷ Try a Trial	2039-03-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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