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Last Updated: May 3, 2024

Claims for Patent: 5,215,895

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Summary for Patent: 5,215,895

Title:	DNA encoding a mammalian cytokine, interleukin-11
Abstract:	A novel mammalian cytokine, IL-11, and processes for producing it are disclosed. IL-11 may be used in pharmaceutical preparations for stimulating and/or enhancing cells involved in the immune response and cells involved in the proper functioning of the hematopoietic system.
Inventor(s):	Bennett; Frances K. (Melrose, MA), Paul; Stephen R. (Boston, MA), Yang; Yu-Chung (Indianapolis, IN)
Assignee:	Genetics Institute, Inc. (Cambridge, MA)
Application Number:	07/526,474
Patent Claims:	1. An isolated DNA sequence that codes an expression for an amino acid sequence selected from the group consisting of: (a) amino acid 21 through amino acid 199 of the primate sequence of FIG. 3; (b) amino acid 21 through amino acid 199 of the human sequence of FIG. 3; (c) amino acid 1 through amino acid 199 of the primate sequence of FIG. 3; and (d) amino acid 1 through amino acid 199 of the human sequence of FIG. 3. 2. An isolated DNA sequence that codes on expression for an amino acid sequence comprising amino acid 21 through amino acid 199 of the human sequence of FIG. 3. 3. A DNA sequence that codes on expression for an amino acid sequence comprising amino acid 1 through amino acid 199 of the human sequence of FIG. 3. 4. A plasmid vector comprising a DNA sequence of claim 1 or claim 2. 5. A cell transformed with a DNA sequence of claim 1 or claim 2 in operative association with an expression control sequence capable of directing replication and expression of said DNA sequence. 6. The cell according to claim 5 wherein the cell is a mammalian or bacterial cell. 7. A process for producing an IL-11 protein comprising culturing a cell of claim 5 in a suitable culture medium and isolating said I1-11 protein from said cell.

Details for Patent 5,215,895

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Wyeth Pharmaceuticals Inc.	NEUMEGA	oprelvekin	For Injection	103694	11/25/1997	⤷ Try a Trial	2010-06-01
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,215,895

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	9107495	⤷ Try a Trial
United States of America	6066317	⤷ Try a Trial
United States of America	5854028	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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