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Last Updated: December 18, 2025

Claims for Patent: 4,481,189


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Summary for Patent: 4,481,189
Title:Process for preparing sterilized plasma and plasma derivatives
Abstract:A mammalian blood plasma or plasma derivative substantially free of active hepatitis B or non-A, non-B viruses is disclosed, the plasma being characterized by the presence of factor VIII, the percent by weight of denatured factor VIII to the sum of undenatured factor VIII and denatured factor VIII being less than 50%. The plasma is sterilized by contact with a detergent, alcohol or ether, preferably a mixture of detergent and ether, usually followed by removal of the viral sterilizing agent.
Inventor(s):Alfred M. Prince
Assignee: New York Blood Center Inc
Application Number:US06/368,250

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