Claims for Patent: 3,749,556

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Summary for Patent: 3,749,556

Title:	Radiopharmaceutical generator kit
Abstract:	A KIT READILY ASSEMBLED INTO ESSENTIALLY A PACKED CHROMATOGRAPHIC COLUMN FOR GENERATING TECHNETIUM-99M LABELED PHARMACEUTICALS IN A SIMPLE TWO-STEP PROCESS. TECHNETIUM-99M PERTECHNETATE IN A FIRST STEP IS ISOLATED AND ITS VALENCE STATE REDUCED BY ADSORPTION UPON A REDUCING AGENT. THEN THE REDUCED TECHNETIUM-99M IN A SECOND STEP IS ELUTED FROM THE REDUCING AGENT BY COMBINATION WITH AN IMMEDIATELY LABELED BIOLOGICAL COMPOUND, THE ELUANT PH IS ADJUSTED AND BUFFERED TO PHYSIOLOGICAL LEVELS AND BENIGN CATIONS ARE SUBSTITUTED FOR UNCOMBINED REDUCING AGENT AND ISOTOPE IONS. A NEW TECHNETIUM-99M LABELED RADIOPHARMACEUTICAL USEFUL IN LIVER IMAGING IS PRODUCED BY INTERACTION WITH THE COLUMN PACKING IN ONE SPECIFIC ASPECT OF THE PROCEDURE. D R A W I N G
Inventor(s):	M Barak, H Winchell
Assignee:	US Department of Energy
Application Number:	US00173099A

Details for Patent 3,749,556

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Cis Bio International	PULMOTECH MAA	kit for the preparation of technetium tc-99m albumin aggregated	For Injectable Suspension	210089	March 20, 2020	⤷ Get Started Free	1991-08-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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