Claims for Patent: 12,233,126

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Summary for Patent: 12,233,126

Title:	High concentration immunoglobulin composition for pharmaceutical application
Abstract:	The present invention relates to a liquid composition comprising polyclonal immunoglobulins, at least one viscosity modulating amino acid, selected from arginine and histidine, and at least one stabilising amino acid, selected from glycine and proline, wherein more than 90% of the polyclonal immunoglobulins are in the form of monomers or dimers and less than 5% in the form of polymers, and wherein the immunoglobulin concentration in the composition is above 160 g/L and the pH is in the range from 5.2 to 5.9. The invention further relates to a liquid composition for use in medical treatment, to amino acids for formulating a highly concentrated polyclonal immunoglobulins as well as a method of formulating.
Inventor(s):	Karin Ahrer, Waltraud Kaar, Ulrich Roessl
Assignee:	Octapharma AG
Application Number:	US17/519,141

Details for Patent 12,233,126

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h.	OCTAGAM	immune globulin intravenous (human)	Injection	125062	May 21, 2004	12,233,126	2041-11-04
Octapharma Pharmazeutika Produktionsges.m.b.h.	OCTAGAM	immune globulin intravenous (human)	Injection	125062	March 26, 2007	12,233,126	2041-11-04
Octapharma Pharmazeutika Produktionsges.m.b.h.	OCTAGAM	immune globulin intravenous (human)	Injection	125062	July 11, 2014	12,233,126	2041-11-04
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 12,233,126

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2017212067	⤷ Get Started Free
United States of America	2022233692	⤷ Get Started Free
United States of America	2019125868	⤷ Get Started Free
United States of America	11191833	⤷ Get Started Free
Russian Federation	2749953	⤷ Get Started Free
Russian Federation	2018146817	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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