Claims for Patent: 12,128,100

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Summary for Patent: 12,128,100

Title:	Immunogenic compositions for treatment of Hepatitis B
Abstract:	The present disclosure provides compositions and methods useful for inducing a The cell response in a subject suffering from Hepatitis B. As described herein, the compositions of the disclosure comprise HBsAg having S, Pre-S1 and Pre-S2 proteins and an aluminum phosphate adjuvant. In a preferred embodiment, the immunogenic composition comprises at least 20 μg/ml of HBsAg antigen and the amount of non-adsorbed antigen is at least 30%.
Inventor(s):	David Evander Anderson, Tanvir Ahmed
Assignee:	Brii Biosciences Inc
Application Number:	US17/293,431

Details for Patent 12,128,100

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Vbi Vaccines (delaware), Inc.	PREHEVBRIO	hepatitis b vaccine (recombinant)	For Injection	125737	November 30, 2021	⤷ Start Trial	2039-11-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 12,128,100

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Country	Patent Number	Estimated Expiration
South Africa	202103976	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2020099927	⤷ Start Trial
United States of America	2025269013	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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