Claims for Patent: 11,696,956

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Summary for Patent: 11,696,956

Title:	Bicyclic peptide ligands specific for EphA2
Abstract:	The present invention relates to polypeptides which are covalently bound to non-aromatic molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of the Eph receptor tyrosine kinase A2 (EphA2). The invention also includes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups, to pharmaceutical compositions comprising said peptide ligands and drug conjugates and to the use of said peptide ligands and drug conjugates in preventing, suppressing or treating a disease or disorder characterised by overexpression of EphA2 in diseased tissue (such as a tumour).
Inventor(s):	Liuhong Chen, Philip Huxley, Silvia PAVAN, Katerine Van Rietschoten
Assignee:	BicycleTx Ltd
Application Number:	US16/771,186

Details for Patent 11,696,956

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Seqirus Inc.	AGRIFLU	influenza virus vaccine	Injection	125297	November 27, 2009	⤷ Get Started Free	2038-12-19
Novo Nordisk Inc.	XULTOPHY 100/3.6	insulin degludec and liraglutide	Injection	208583	November 21, 2016	⤷ Get Started Free	2038-12-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,696,956

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2019122863	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2019122860	⤷ Get Started Free
United States of America	2024189436	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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