Claims for Patent: 11,685,917

✉ Email this page to a colleague

Summary for Patent: 11,685,917

Title:	Functional genomics using CRISPR-Cas systems for saturating mutagenesis of non-coding elements, compositions, methods, libraries and applications thereof
Abstract:	The application relates to a deep scanning mutagenesis library to interrogate phenotypic changes in a population of cells comprising a plurality of CRISPR-Cas system guide RNAs targeting genomic sequences within at least one continuous genomic region, wherein the guide RNAs target at least 100 genomic sequences upstream of a PAM sequence for every 1000 base pairs within the continuous genomic region and methods for their use.
Inventor(s):	Daniel E. BAUER, Stuart H. Orkin, Neville Espi Sanjana, Ophir SHALEM, Jason Wright, Feng Zhang
Assignee:	Boston Childrens Hospital , Massachusetts Institute of Technology , Broad Institute Inc
Application Number:	US15/807,007

Details for Patent 11,685,917

Glossary

Subscribe to access the full database, or Get Started Free
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Vertex Pharmaceuticals Inc	CASGEVY	exagamglogene autotemcel	Suspension	125787	December 08, 2023	11,685,917	2037-11-08
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,685,917

Subscribe to access the full database, or Get Started Free
Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2016182917	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2016182893	⤷ Get Started Free
United States of America	2024167018	⤷ Get Started Free
United States of America	2024102004	⤷ Get Started Free
United States of America	2023235285	⤷ Get Started Free
United States of America	2018171297	⤷ Get Started Free
United States of America	2018119138	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.