Last Updated: April 23, 2026

Claims for Patent: 11,654,157

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Summary for Patent: 11,654,157

Title:	Methods and compositions for cancer therapies that include delivery of halogenated thymidines and thymidine phosphorylase inhibitors in combination with radiation
Abstract:	Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
Inventor(s):	Scott Grindrod, Mira Jung, Olga Timofeeva, Milton Brown, Anatoly Dritschilo
Assignee:	Shuttle Pharmaceuticals Inc
Application Number:	US16/475,999

Details for Patent 11,654,157

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Modernatx, Inc.	SPIKEVAX	covid-19 vaccine, mrna	Injection	125752	January 31, 2022	11,654,157	2038-01-09
Modernatx, Inc.	SPIKEVAX	covid-19 vaccine, mrna	Injection	125752	September 11, 2023	11,654,157	2038-01-09
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,654,157

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Country	Patent Number	Estimated Expiration
Canada	3049251	⤷ Start Trial
European Patent Office	3565557	⤷ Start Trial
United States of America	12357650	⤷ Start Trial
United States of America	2019343859	⤷ Start Trial
United States of America	2023302034	⤷ Start Trial
United States of America	2024226129	⤷ Start Trial
United States of America	2025302857	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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