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Last Updated: December 18, 2025

Claims for Patent: 11,441,188

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Summary for Patent: 11,441,188

Title:	Methods for detecting DNA mutations using Mitra tip extraction
Abstract:	The present disclosure provides rapid and non-invasive methods for determining whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on detecting hereditary cancer-related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device (e.g., MITRA Tip). Kits for use in practicing the methods are also provided.
Inventor(s):	Sanders Heather, Clarke Nigel J.
Assignee:	Quest Diagnostics Investments LLC
Application Number:	US15811515
Patent Claims:

Details for Patent 11,441,188

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Llc	INTRON A	interferon alfa-2b	For Injection	103132	June 04, 1986	11,441,188	2037-11-13
Merck Sharp & Dohme Llc	INTRON A	interferon alfa-2b	For Injection	103132		11,441,188	2037-11-13
Merck Sharp & Dohme Llc	INTRON A	interferon alfa-2b	Injection	103132		11,441,188	2037-11-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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