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Last Updated: April 16, 2026

Claims for Patent: 11,377,484

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Summary for Patent: 11,377,484

Title:	Compounds to inhibit bacterial s-layer protein assembly
Abstract:	The present invention relates to the field of bacterial Surface (S)-layer proteins, in particular to compounds capable of disrupting the bacterial S-Layer, specifically the S-Layer of Bacillus anthracis. More particularly, the invention provides for single domain antibodies for diagnosis and treatment of infection caused by pathogens with an S-Layer, in particular of Bacillus anthracis infection. The invention relates to S-Layer protein binding agents inhibiting bacterial growth and interrupting S-Layer assembly, useful in the treatment of bacterial infection, more specifically treatment of anthrax disease.
Inventor(s):	Han Remaut, Antonella Fioravanti
Assignee:	Vrij Universiteit Brussel , Vlaams Instituut voor Biotechnologie VIB , Vrije Universiteit Brussel VUB
Application Number:	US16/651,713

Details for Patent 11,377,484

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Eli Lilly And Company	TALTZ	ixekizumab	Injection	125521	March 22, 2016	⤷ Start Trial	2038-10-02
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,377,484

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Country	Patent Number	Estimated Expiration
Canada	3076250	⤷ Start Trial
European Patent Office	3691684	⤷ Start Trial
United Kingdom	201716059	⤷ Start Trial
United States of America	2020255501	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2019068677	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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