Claims for Patent: 11,274,301

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Summary for Patent: 11,274,301

Title:	Micro-RNA inhibitors and their uses in disease
Abstract:	The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oligonucleotides, including locked nucleic acids (LNAs).
Inventor(s):	Pier Paolo Pandolfi, Laura Poliseno, Yvonne Tay, Leonardo Salmena
Assignee:	Beth Israel Deaconess Medical Center Inc
Application Number:	US15/727,156

Details for Patent 11,274,301

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bluebird Bio Inc.	SKYSONA	elivaldogene autotemcel	Injection	125755	September 16, 2022	11,274,301	2037-10-06
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,274,301

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2012142313	⤷ Get Started Free
United States of America	2018073025	⤷ Get Started Free
United States of America	2015126579	⤷ Get Started Free
United States of America	10131905	⤷ Get Started Free
Japan	2014515024	⤷ Get Started Free
European Patent Office	3159410	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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