Last Updated: June 25, 2026

Claims for Patent: 11,260,113

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Summary for Patent: 11,260,113

Title:	NK-lysin peptide compositions and methods for their use as antimicrobial/antiviral agents
Abstract:	Natural killer (NK)-lysin peptides from chicken, bovine and human species are used as an antimicrobial or antiviral agent alone or in combination with other agents. A pharmaceutical composition comprising NK-lysin peptides was effective against Rotavirus and various gram-negative and gram-positive bacteria that were tested. Combinations of NK-lysin peptides plus silver nanoparticles or IL-2 were also effective against Salmonella typhimurium. Treatment with the NK-lysin peptides repressed β-lactam-resistance genes (CTX-M-1, CTX-M-8 and CTX-M-9) in bacterial species tested and thus can be used to augment treatment with β-lactams and increase bacterial sensitivity to this important class of antibiotics.
Inventor(s):	Maged Mostafa Mahmoud, Haitham A. Yacoub, Ahmed M. Al-Hejin, Turki Abujaml, Sherif Abd-Elmaksoud
Assignee:	King Abdulaziz University
Application Number:	US17/213,483

Details for Patent 11,260,113

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Biologicals	AREXVY	respiratory syncytial virus vaccine, adjuvanted	For Injection	125775	May 03, 2023	⤷ Start Trial	2041-03-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,260,113

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Country	Patent Number	Estimated Expiration
United States of America	11433122	⤷ Start Trial
United States of America	2022305093	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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