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Last Updated: December 28, 2025

Claims for Patent: 11,053,280


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Summary for Patent: 11,053,280
Title:Anti-VEGF protein compositions and methods for producing the same
Abstract:The present disclosure pertains to compositions comprising aflibercept and methods for producing such compositions in chemically defined media and using chromatography to reduce amounts of certain aflibercept variants.
Inventor(s):Tustian Andrew, Vartak Ankit, Daly Thomas, Pyles Erica, Palackal Nisha, Wang Shunhai, Li Ning
Assignee:Regeneron Pharmaceuticals, Inc.
Application Number:US16996007
Patent Claims:

Details for Patent 11,053,280

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 November 18, 2011 ⤷  Get Started Free 2040-08-18
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 August 16, 2018 ⤷  Get Started Free 2040-08-18
Regeneron Pharmaceuticals, Inc. EYLEA HD aflibercept Injection 761355 August 18, 2023 ⤷  Get Started Free 2040-08-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 11,053,280

Country Patent Number Estimated Expiration
South Africa 202208710 ⤷  Get Started Free
South Africa 202107647 ⤷  Get Started Free
South Africa 202107646 ⤷  Get Started Free
South Africa 202107644 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2021113591 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2021112929 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2021112928 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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