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Last Updated: December 16, 2025

Claims for Patent: 11,041,149

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Summary for Patent: 11,041,149

Title:	PH20 polypeptide variants, formulations and uses thereof
Abstract:	Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
Inventor(s):	Wei Ge, Shepard H. Michael, Zhao Qiping, Connor Robert James
Assignee:	Halozyme, Inc.
Application Number:	US16824572
Patent Claims:

Details for Patent 11,041,149

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	May 05, 2004	⤷ Get Started Free	2040-03-19
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	December 02, 2004	⤷ Get Started Free	2040-03-19
Amphastar Pharmaceuticals, Inc.	AMPHADASE	hyaluronidase	Injection	021665	October 26, 2004	⤷ Get Started Free	2040-03-19
Akorn, Inc.	HYDASE	hyaluronidase	Injection	021716	October 25, 2005	⤷ Get Started Free	2040-03-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,041,149

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2013102144	⤷ Get Started Free
United States of America	9447401	⤷ Get Started Free
United States of America	2025197836	⤷ Get Started Free
United States of America	2025197835	⤷ Get Started Free
United States of America	2025197834	⤷ Get Started Free
United States of America	2025197833	⤷ Get Started Free
United States of America	2025197832	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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