Claims for Patent: 10,954,549

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Summary for Patent: 10,954,549

Title:	Detection and classification of an anticoagulant using a clotting assay
Abstract:	In some embodiments, the invention provides methods for detecting and/or classifying an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control clotting measurement; and subjecting a sample of a blood component from a patient suspected of having the anticoagulant to the clotting assay in the presence of the Factor Xa reagent to obtain a patient clotting measurement, wherein the patient clotting measurement sample greater than the control clotting measurement indicates the presence of the anticoagulant at a therapeutically relevant amount or higher in the patient. In some embodiments, the invention includes methods for classifying an anticoagulant as an anti-Factor Xa or a direct thrombin inhibitor anticoagulant using a clotting assay in the presence of an ecarin reagent.
Inventor(s):	Zaman Fowzia S., Doubleday Marc
Assignee:	Haemonetics Corporation
Application Number:	US16674334
Patent Claims:

Details for Patent 10,954,549

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Astrazeneca Ab	ANDEXXA	coagulation factor xa (recombinant), inactivated-zhzo	Injection	125586	May 03, 2018	10,954,549	2039-11-05
Astrazeneca Ab	ANDEXXA	coagulation factor xa (recombinant), inactivated-zhzo	Injection	125586	December 31, 2018	10,954,549	2039-11-05
Boehringer Ingelheim Pharmaceuticals, Inc.	PRAXBIND	idarucizumab	Injection	761025	October 16, 2015	10,954,549	2039-11-05
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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