Claims for Patent: 10,889,630

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Summary for Patent: 10,889,630

Title:	Method of separating Factor VIII from blood products
Abstract:	The invention provides a method for separating a Factor VIII (FVIII) protein from a first composition comprising the FVIII protein, which contains at least the light chain of FVIII, and a von-Willebrand-Factor (vWF) protein which comprises at least the FVIII binding domain of vWF, wherein the FVIII protein can form a complex with the vWF protein, the method comprising the steps: contacting the first composition with an affinity resin comprising a ligand and a matrix, wherein the ligand has an affinity to the light chain of FVIII, and separating the affinity resin from the mixture to obtain a modified first composition and a second composition, wherein the second composition contains the affinity resin, and a complex of the FVIII protein and the vWF protein.
Inventor(s):	Stefan Winge, Per Rosen, Alex SCHEEPERS
Assignee:	Octapharma AG
Application Number:	US16/077,195

Details for Patent 10,889,630

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h.	OCTAPLAS	pooled plasma (human), solvent/detergent treated	For Injection	125416	January 17, 2013	10,889,630	2037-02-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,889,630

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Country	Patent Number	Estimated Expiration
Australia	2017218581	⤷ Start Trial
Brazil	112018016336	⤷ Start Trial
Canada	3013662	⤷ Start Trial
China	108699133	⤷ Start Trial
European Patent Office	3205665	⤷ Start Trial
European Patent Office	3414264	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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