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Last Updated: December 18, 2025

Claims for Patent: 10,888,601


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Summary for Patent: 10,888,601
Title:Use of a VEGF antagonist to treat angiogenic eye disorders
Abstract:The present invention provides methods for treating angiogenic eye disorders by sequentially administering multiple doses of a VEGF antagonist to a patient. The methods of the present invention include the administration of multiple doses of a VEGF antagonist to a patient at a frequency of once every 8 or more weeks. The methods of the present invention are useful for the treatment of angiogenic eye disorders such as age related macular degeneration, diabetic retinopathy, diabetic macular edema, central retinal vein occlusion, branch retinal vein occlusion, and corneal neovascularization.
Inventor(s):Yancopoulos George D.
Assignee:REGENERON PHARMACEUTICALS, INC.
Application Number:US16397267
Patent Claims:

Details for Patent 10,888,601

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 November 18, 2011 ⤷  Get Started Free 2039-04-29
Regeneron Pharmaceuticals, Inc. EYLEA aflibercept Injection 125387 August 16, 2018 ⤷  Get Started Free 2039-04-29
Regeneron Pharmaceuticals, Inc. EYLEA HD aflibercept Injection 761355 August 18, 2023 ⤷  Get Started Free 2039-04-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 10,888,601

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2012097019 ⤷  Get Started Free
United States of America 9669069 ⤷  Get Started Free
United States of America 9254338 ⤷  Get Started Free
United States of America 2025152669 ⤷  Get Started Free
United States of America 2024123030 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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