Last Updated: May 11, 2026

Claims for Patent: 10,842,858

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Summary for Patent: 10,842,858

Title:	Compositions and methods of enhancing immune responses to Eimeria
Abstract:	Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.
Inventor(s):	Walter Bottje, Billy Hargis, Luc Berghman, Young Min Kwon, Kimberly Cole, Mandy Cox, Sherryll Layton, Saeed El-Ashram, John Barta, Guillermo Tellez
Assignee:	Texas A&M University , University of Arkansas at Little Rock
Application Number:	US16/028,599

Details for Patent 10,842,858

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Emergent Product Development Gaithersburg, Inc.	ACAM2000	smallpox (vaccinia) vaccine, live	For Injection	125158	August 31, 2007	10,842,858	2038-07-06
Novo Nordisk Inc.	XULTOPHY 100/3.6	insulin degludec and liraglutide	Injection	208583	November 21, 2016	10,842,858	2038-07-06
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,842,858

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2009059298	⤷ Start Trial
United States of America	8956849	⤷ Start Trial
United States of America	2018333474	⤷ Start Trial
United States of America	2015216954	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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